As the semiconductor industry becomes more digital and interconnected, it faces a dual challenge: the rise of sophisticated cyber threats and the rapid expansion of global cybersecurity regulations. Operational Technology (OT)—the systems that control critical manufacturing processes—has become a primary target for cyberattacks capable of disrupting production, compromising intellectual property, and impacting business continuity. In response, industry bodies and regulatory authorities have introduced new standards such as SEMI E187 and E188, along with broader frameworks like IEC 62443 and guidance from the National Institute of Standards and Technology (NIST). Navigating these new requirements while protecting operations from emerging threats is now a strategic imperative for manufacturers. This session offers business and technology leaders a practical roadmap for strengthening cybersecurity in semiconductor environments through a clear alignment between risk management and regulatory compliance. The session begins by exploring today’s cyber threat landscape, with real-world examples that illustrate how attackers are targeting semiconductor operations and the business impact of those incidents. These cases underline the urgency for proactive and integrated cybersecurity strategies that go beyond technical controls. Attendees will learn how organizations are translating regulatory requirements into realistic, scalable strategies that reflect operational realities. The discussion will highlight how companies are improving visibility over critical assets, enhancing their ability to respond to incidents, and fostering stronger collaboration between IT, OT, and compliance teams. Importantly, it will also address how leading manufacturers are balancing cybersecurity investments (CAPEX) by aligning capital and operational (OPEX) spending with both compliance goals and broader business outcomes. The session also explores the strategic role of artificial intelligence (AI) and data analytics in cybersecurity—especially their ability to detect anomalies, predict threats, and support faster, smarter decision-making. These capabilities are becoming essential as regulatory expectations evolve and threats become more dynamic. Participants will walk away with a strong understanding of how to approach cybersecurity not simply as a technical necessity, but as a core component of operational resilience and business strategy. Whether adapting to new regulations or mitigating high-impact risks, this session will provide valuable insights for decision-makers seeking to protect their organizations while driving performance in a highly competitive global market.